First Aid Information For:

Prestone DOT 3 Synthetic Hi-Temp Brake Fluid, AS400Y-08/01/2018

Eye Contact: Exposed eyes should be immediately flushed with copious amounts of water using a steady stream for a minimum of 20 minutes. Seek immediate medical attention.

Skin Contact: Remove contaminated clothing. Wash all affected and exposed areas with soap and water. If skin irritation or redness develops or persists, seek medical attention.

Inhalation: Remove to fresh air if effects occur and seek medical attention.

Ingestion: If swallowed, get immediate medical advice by calling a Poison Control Center or hospital emergency room. If advice is not available, take victim and product container to the nearest emergency treatment center or hospital. Do not attempt to give anything by mouth to an unconscious person.

Notes to Physician: It is estimated that the lethal oral dose of diethylene glycol in adults is 1.0-1.2 ml/kg. Diethylene glycol may cause an elevated anion-gap metabolic acidosis and renal tubular injury. Liver injury may occur, but not as severe as kidney injury. The signs and symptoms in diethylene glycol poisoning are those of metabolic acidosis, CNS depression and kidney injury. Urinalysis may show albuminuria, hematuria and oxaluria. The current medical management of diethylene glycol poisoning includes elimination of diethylene glycol, correction of metabolic acidosis and prevention of kidney injury. It is essential to have immediate and follow-up urinalysis and clinical chemistry. There should be particular emphasis on acid-base balance, and liver and kidney function tests. For severe and/or deteriorating cases, hemodialyis may be required. Dialysis should be considered for patients who have severe metabolic acidosis, or compromise of renal function. There is no conclusive evidence that ethanol treatment will be beneficial. 4-Methyl pyrazole (Fomepizole) shows some promise as treatment because of its apparent lack of toxicity. Consult your poison control center.