First Aid Information For: Zerex Extended Life Antifreeze -Coolant

Eye contact: If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. Do not remove the victim from water access for transport to a medical facility unless instructed to do so by qualified medical personnel. If possible, continue flushing the eye gently with water while transporting the victim.
Skin: Remove contaminated clothing. Flush exposed area with large amounts of water. If skin is damaged, seek immediate medical attention. If skin is not damaged and symptoms persist, seek medical attention. Launder clothing before reuse.
Ingestion: Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation: If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Notes to Physician
Hazards: Effects of acute ethylene glycol poisoning appear in three fairly distinct stages. The initial stage occurs shortly after exposure, lasts 6-12 hours, and is characterized by central nervous system effects (transient exhilaration, nausea, vomiting, and in severe cases, coma, convulsions, and possible death). The second stage lasts from 12-36 hours after exposure and is initiated by the onset of coma. This phase is characterized by tachypnia, tachycardia, mild hypotension, cyanosis, and in severe cases, pulmonary edema, bronchopneumonia, cardiac enlargement, and congestive failure. The final stage occurs 24-72 post-exposure and is characterized by renal failure, ranging from a mild increase in blood urea nitrogen and creatinine followed by recovery, to complete anuria with acute tubular necrosis that can lead to death. Oxaluria is found in most cases. The most significant laboratory finding in ethylene glycol intoxication is severe metabolic acidosis. Ingestion or other significant exposure to this material (or a component) may cause metabolic acidosis.
Treatment: This product contains ethylene glycol. Ethanol decreases the metabolism of ethylene glycol to toxic metabolites. Ethanol should be administered as soon as possible in cases of severe poisoning since the elimination half-life of ethylene glycol is 3 hours. If medical care will be delayed several hours, give the patient three to four 1-ounce oral "shots" of 86-proof or higher whiskey before or during transport to the hospital. Fomepizole (4-methylpyrazole) is an effective antagonist of alcohol dehydrogenase, and as such, may be used as an antidote in the treatment of ethylene glycol poisoning. Hemodialysis effectively removes ethylene glycol and its metabolites from the body. Fomepizole (4-methylpyrazole) is an effective antagonist of alcohol dehydrogenase, and as such, may be used as an antidote in the treatment of ethylene glycol, diethylene glycol and methanol poisoning.